Chloroquine Phosphate Injection

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Chloroquine Phosphate Injection

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Chloroquine Phosphate Injection

Product description

Details:

Chloroquine is an antimalarial used to treat acute malarial attacks. It can be used for preventing malaria from Plasmodium Vivax, P. ovale and P. malariae although many areas of the world have strains resistant to P. falciparum in which cases other antimalarials should be used. Chloroquine is a 4-aminoquinalone which has rapid schizontocidal activity against blood forms of P. ovale and P. malariae and also against susceptible strains of P. vivax and P. falciparum.

Product Packaging
Chloroquine Phosphate Injection is typically produced in 5ml ampoules can be packaged as:
10 ampoules / tray / box,
10 ampoules / tray, 10 tray / box,
or according to the customer's requirements
  • Antimalarial
  • Vitamin B12
  • China
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Product Dosages

    

NameFormDosageCode
Chloroquine Phosphate Injection 64.5mg/5ml 1000.1483
Chloroquine Phosphate Injection 200mg/5ml 1000.1356
Chloroquine Phosphate  Injection  250mg/5ml  1000.1448
Chloroquine Phosphate Injection  322mg/5ml 1000.1226
Chloroquine Phosphate  Injection  486mg/5ml 1000.1396
Additional Information

Chloroquine Phosphate injection


DESCRIPTION:

It is a clear sterile solution of Chloroquine Phosphate Each ampoule of 2 ml contains

129 mg Chloroquine Phosphate (approximately equivalent to 80 mg Chloroquine base),

Each ampoule of 5 ml contains 250 mg Chloroquine Phosphate (approximately equivalent

to 155mg Chloroquine base) or each ampoule of 5 ml contains 322.5 mg Chloroquine

Phosphate (approximately equivalent to 200 mg Chloroquine base).

 

ACTIONS AND USES:

Chloroquine Phosphate injection is one of the most powerful and rapid acting

antimalarials. It can kill the asexual forms of various malaria protozoa and is highly effective

in the control of the clinical symptoms of malignant tertian and quartan malaria. It is mainly

used to rescue severe malarial patients or those unable to take medicine orally. In case of

vomiting or other causes. Chloroquine Phosphate is readily absorbed in the human body

and a considerable proportion is retained in the tissue cells of the internal organs, and it is

excreted slowly.

 

ADMINISTRATION AND DOSAGE:

The dosage of this drug should be calculated strictly according to the body weight of

the patients, especially for children, and it should be reduced adequately for children with

general weakness, for babies or old patients. Chloroquine phosphate injection should not

be used or should be used with great care in Patients with severe hepatic, renal or cardiac

diseases.

 

By intramuscular injection:

Children: 2-3mg of Chloroquine base per kg body weight once daily. For the sake of

safety, this daily dose may be given in two injections at half an hour interval.

Adults: Usually once daily, 2-3 mg Chloroquine base per kg body weight and may be

repeated after 8 hours, the total daily dose should not exceed 6 mg (base) per kg body

weight.

 

By intravenous instillation:

This method of administration is only applied for rescuing patients with cerebral malaria

or in emergency. A dose of 2-3mg of Chloroquine base per kg body weight is diluted with

thorough shaking in 500 ml isotonic sodium chloride solution or 5% dextrose solution and

is then injected slowly at a rate of NOT MORE THAN 20 DRIPS PER MINUTE FOR

CHILDREN and NOT MORE THAN 40 DRIPS PER MINUTE FOR ADULTS. This dose

may be repeated after 8 hours, but the total daily dose should not exceed 6 mg (base) per kg

body weight. The dosage for any adult patient over 50 kg is calculated according to 50 kg

body weight.

 

SIDE-EFFECTS:

Chloroquine Phosphate Injection may cause a temporary fall of blood pressure, increase

of pulse rate and adverse reactions such as vertigo, headache, nausea, vomiting, obscure

vision and local pain.

 

PRECAUTIONS:

1. Chloroquine Phosphate Injection, if given in over dose or injected too rapidly, may

produce severe toxic effect. For this reason, the injection should only be used in patients

who are unable to take medicine orally, close attention must be paid to avoiding over dose.

In intramuscular injection, be sure that the drug is not injected into the blood vessel. As

soon as the patient becomes better and is able to swallow, oral doses of Chloroquine Tablets

or Syrup should be given instead.

2. Chloroquine Phosphate Injection should not be mixed with drug like Quinine

Dihydrochloride which will cause a fall of blood pressure and at the same time no other

antimalarial drug should be used.

3. After injection of Chloroquine Phosphate, for safety sake, the patient should rest for

half an hour under medical care in the clinic.

 

PACKING:

In boxes of 10 or 50 ampoules of 2 ml containing 129 mg Chloroquine Phosphate (80 mg

base), in boxes of 5 or 100 ampoules of 5 ml containing 250mg Chloroquine

Phosphate (155mg base) or in boxes of 5 or 100 ampoules of 5ml containing 322.5 mg

Chloroquine Phosphate (200 mg base).

 

STORAGE:

It should be kept in well-closed containers and protected from light.






Mercator's Other popular Antimalarial products according to the WHO guidelines include: 

1. Arteether Injection
2  Artemether + Lumefantrine Powder for Suspension
3. Artemether + Lumefantrine Tablets
4. Artemether Injection
5. Artemisinin + Piperaquine Tablets
6. Artesunate + Amodiaquine Tablets
7. Artesunate + Mefloquine Tablets
8. Artesunate + Sulfadoxine + Pyrimethamine Tablets
9. Chloroquine Phosphate Injection
10. Dihydroartemisinin + Piperaquine Phosphate + Trimethoprim Powder for Suspension
11. Dihydroartemisinin + Piperaquine Phosphate + Trimethoprim Tablets
12. Dihydroartemisinin + Piperaquine Phosphate Powder for Suspension
13 Dihydroartemisinin + Piperaquine Phosphate Tablets
14. Quinine Dihydrochloride Injection
15. Sulfadoxine + Pyrimethamine Tablets



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